We discuss whether one should expect that multiply imaged QSOs can be
understood with `simple' lens models which contain a handful of parameters.
Whereas for many lens systems such simple mass models yield a remarkably good
description of the observed properties, there are some systems which are
notoriously difficult to understand quantitatively. We argue that at least in
one case (B 1422+231) these difficulties are not due to a `wrong'
parametrization of the lens model, but that the discrepancy between observed
and model-predicted flux ratios are due to substructure in the lens. Similar to
microlensing for optical fluxes, such substructure can distort also the radio
flux ratios predicted by `simple' mass models, in particular for highly
magnified images, without appreciably changing image positions. Substructure
also does not change the time delay significantly and therefore has little
effect on the determination of the Hubble constant using time delays. We
quantify these statements with several simple scenarios for substructure, and
propose a strategy to model lens systems in which substructure is suspected.Comment: plain tex, 13 pages with four figure