术后肠梗阻（postoperativeileus，POI）是机体自身应对手术创伤的一种自限性防御反应，是外科手术中不可避免的并发症。术后肠梗阻延缓了患者术后康复速度，延长住院时间，并可导致多种术后并发症发病率升高，术后肠梗阻导致的的治疗成本与医疗资源消耗，是一项巨额的医疗耗费。近年来，关于术后肠梗阻的研究热度逐渐上升，研究认为术后肠道的炎性反应是导致术后肠梗阻的关键。运用基因敲除技术获得某一基因敲除的小鼠，对比研究该基因于术后肠梗阻发病过程中的病理生理作用，成为研究术后肠梗阻发病机制以及机体对胃肠道保护机制的一项重要的研究方法。类固醇激素受体辅激活子3（Steroidreceptorcoact...Postoperative ileus (POI) is a self-limiting defense response of the body itself to the surgical trauma, which is an unavoidable complication in surgical operation. The primary features of POI include nausea, vomiting, inability to tolerate an oral diet, abdominal distension and delayed exhaust and defecation. Postoperative ileus has be show slow patient recovery, prolonged hospital stay, and also...学位：医学硕士院系专业：医学院_外科学学号：2452014115352
