目的：目前市场上许多可用的单胺类抗抑郁药物起效缓慢且副作用多。以柴胡舒肝散抗抑郁促动力（A&P）为线索，发现阿魏酸和水合橙皮内酯后，仍然不清楚是否还存在A&P的药物，本文以炎性通路为主线，通过氧化应激，犬尿酸，ghrelin等多方面对比研究中药及单体A&P疗效。初步阐明其A&P潜在作用机理，枳壳芍药药对及有效成分辛弗林、芍药苷可能是潜在的天然抗抑郁药物。 方法：1.枳壳芍药药对与辛弗林、芍药苷急性抗抑郁促动力疗效对比：FST实验、TST实验、在体胃肠动力实验；2.慢性抗抑郁促动力疗效对比：FST实验、OFT实验、ELISA试剂盒检测胃动力激素含量；3.血浆和海马中细胞因子含量对比：定量即时P...Objective: At present, many monoamine antidepressants are slow and have a lot of side effects in the market. To CSS A&P as a clue, we find Ferulic Acid and MH, but still do not know whether there is still A&P role. In this study, we focus on inflammatory pathways and compare antidepressant effect and prokinetic effect of ZS and Synephrine and Paeoniflorin from multiple angles through oxidative st...学位：理学硕士院系专业：生命科学学院_细胞生物学学号：2162014115249
