癌症是体内正常细胞突变所引起的一大类疾病,已经成为当今影响人类健康的最主要威胁。目前癌症治疗主要手段仍依赖于化学药物疗法,但是绝大多数化疗药物特异性较差,不易克服体内复杂的生理屏障,并且易诱发癌症多药耐药而导致化疗失败。为了靶向治疗肿瘤,减少药物的毒副作用,克服多药耐药(multidrugresistance,MDR)以达到癌症治疗效果最大化,依托纳米载药传递系统的化疗手段成为极具潜力的研究方向。二十二碳六烯酸(docosahexaenoicacid,DHA)是ω-3多不饱和脂肪酸家族成员之一,具有显著的抗炎抗肿瘤功效。本课题旨在通过探究含有DHA的纳米制剂在肿瘤治疗中的作用功效,为将其开发为...Cancer is a major disease caused by normal cell mutations in the body and has become the most important threat to human health today. At present, the main means of cancer treatment is still dependent on chemical therapy, but the vast majority of chemotherapeutic drugs are less specific, difficult to overcome the complex physiological barrier in the body, and susceptible to induce cancer multid...学位:医学硕士院系专业:药学院_药理学学号:3232014115342