背景和目的：慢性乙型肝炎（ChronichepatitisB，CHB）在世界范围内流行，且经过长时程口服抗病毒治疗后仅有少数患者能达到停药标准。粪菌移植（FecalmicrobiotaTransplantation，FMT）已被证明可以诱导缓解多种临床疾病，包括艰难梭菌相关性结肠炎。在本研究中，我们探索了粪菌移植对长期核苷/酸类似物（nucleos(t)ideanalogues，NAs）治疗后HBeAg仍未实现血清学阴转的CHB患者的治疗价值。 实验方法：在该开放性、单盲、意向性治疗研究中纳入了18例经恩替卡韦（ETV）或替诺福韦（TDF）治疗3年以上但仍未实现HBeAg消失的慢乙肝患者。这...Background and Aims: Chronic hepatitis B (CHB) is a worldwide disease whereas only a small part of patients can achieve the standard of ceasing treatment even after years of oral antiviral therapy. Fecal microbiota transplantation (FMT) has been shown to induce remission in several diseases including Clostridium difficile-related colitis. In this study, we investigated the efficacy of FMT on patie...学位：医学硕士院系专业：医学院_内科学学号：2452014115350
