Separation of vanillin and o-vanillin by three-zone asynchronous simulated moving bed

Abstract

模拟移动床(SimulatedMovingBed,简称SMB)技术作为一种新兴的制备色谱分离技术,经过数十年的发展,已经广泛应用于石油化工、生物医药和食品工业。近几年来,其理论研究主要集中在模型求解、操作方式改进以及操作参数优化设计等方面。本文针对三区带异步切换模拟移动床技术分离邻香兰素与香兰素进行了以下研究工作。 首先,应用一类四阶的紧致差分算法求解SMB模型方程,通过计算实例验证了该算法在空间方向的四阶精度。另外,考察了模型参数对色谱流出曲线的影响。最后,应用该数值方法求解分离葡萄糖和果糖的SMB过程,能够得到准确的模拟结果和快速的计算效率。 其次,应用线性递减惯性因子粒子群算法(L...Simulated Moving Bed is a novel preparative chromatography separation technology, has been widely applied in petrochemical, pharmacy and food industries in past several decades. Recently, the theory research of SMB process focuses on the numerical methods of solving the model equations, improvement of operation modes and optimal design of operating parameters, etc.. In this study, following resear...学位:工程硕士院系专业:化学化工学院_工程硕士(化学工程)学号:2062014115140

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