氧化还原酶(Oxidoreductase)是重要的生物催化剂,其催化的氧化还原反应具有反应条件温和、立体选择性强等优点,但依赖NADH(NADPH)的氧化还原酶需要昂贵的辅酶参与反应。甲酸脱氢酶(FormateDehydrogenase,FDH)在辅酶酶法再生中具有明显优势,甲酸/甲酸脱氢酶再生体系的明显优势在于其唯一副产物CO2对酶的活性没有影响,且易于从反应体系中逃逸出来。苯丙氨酸脱氢酶(PhenylananineDehydrogenase,PheDH),在临床上可用于苯丙酮尿症的检测,且可与甲酸脱氢酶耦联合成苯丙氨酸。 氧化石墨烯(GrapheneOxide,GO)具有独特的片层结构,...Oxidoreductase is one of the most important biocatalysts, which can catalyze reactions with high effienciency and stereoselectivity in mind conditions, but the expensive cofactor is an indispensable part of the reactions. Formate dehydrogenase (FDH) is suitable for the regeneration of cofactor NADH. It has many advantages, namely, favorable thermodynamic equilibrium, the inertness of the substrate...学位:工学硕士院系专业:化学化工学院_生物化工学号:2062014115140