目的 建立Ig/Ig -TCIC的定量方法 ,研究Ig/Ig -TCIC是否具有免疫调节作用。 方法 以Ig的免疫生物学性质和数学计算相结合进行定量。通过研究Ig/Ig-TCIC与C3/Ig -TCIC、全血清和复合Ig与补体等体液免疫指标的关系来探讨其免疫调节作用。结果 成功地建立了Ig/Ig -TCIC的定量方法 ,并发现Ig/Ig -TCIC与有关体液免疫指标的相互关系具有明显规律性。结论 本定量法简便实用。Ig/Ig -TCIC作为免疫网络的中间产物在免疫调节中起重要作用Objective To establish a quantitative method to Ig/Ig two component determined circulating imune complexes(Ig/Ig-TCIC) and study whether Ig/Ig-TCIC was related to the function of immune regulation.Methods Quantity of Ig/Ig-TCIC was carried out by the combination of Ig immune biology with mathematics.The immune regulation of Ig/Ig-TCIC was characterized by the correlation of Ig/Ig-TCIC with C3/Ig-TCIC,serum Ig and C3,and complexed Ig and C3.Results The quantitative method was established and significant regularity was found from the association of Ig/Ig-TCIC with these humoral immune markers.Conclusion This quantitative method was simple and useful.Ig/Ig-TCIC plays an important role in immune regulation as a middle product of immune network.教育部优秀骨干教师基金;; 福建省自然科学基金资助项目(C970 16
