报道了实验室研制的电喷雾离子源 ,具有射频四极杆接口的高分辨飞行时间质谱 (ESI- QQQ- TOFMS)仪器。该仪器具有以下特点 :在离子调制区使用三组四极杆 ,有效地减少离子束的空间分散和能量分散 ;采用正负双脉冲推斥和离子垂直引入方式 ;经过优化设计的二级有网反射器 ;新颖的 MCP安装方法。经初步调试 ,该仪器的分辨本领已优于 1 0 ,0 0 0 ,质量测定精度优于 1 0× 1 0 - 6 。该仪器于 2 0 0 2年 6月通过了国家教育部科技成果鉴定 [鉴字 [教 2 0 0 2 ]第 0 0 8号 ],其主要性能指标已经达到了国际先进水平An high resolution ESI QQQ TOFMS coupled with three sect quadrupoles is reported.The home made instrument in the laboratory has a number of features. It can be used as tandem MS (MS/MS) owing to three sect quadrupoles used in the ion modulation part; the TOFMS analyzer adopted positive negative double extrusion pulse and orthogonal injection way; two grade ion reflector with grids designed by computer simulation, and new micro channel plate (MCP) mounting method. This instrument has already been in working condition after preliminary adjustment, and the resolution over 10,000 was achieved.国家自然科学基金资助项目 (专项 H-2 992 70 0 2和重点 2 92 45 110 ) ;; 教育部现代分析科学重点实验室开放课
