以4-氨基安替比林为模板分子,甲基丙烯酸为功能单体,十二醇/甲苯为溶剂,采用沉淀聚合法制备了对模板分子具有特异吸附的分子印迹聚合物,考察了制备条件,如溶剂用量、功能单体浓度和交联剂浓度对聚合物吸附性能的影响.静态吸附实验结果表明,在模板分子与功能单体、交联剂摩尔比为1∶5∶20的条件下,可制备出吸附量大且特异性识别能力较佳的分子印迹聚合物,对4-氨基安替比林及其结构类似物安替比林的分离因子为3.72.Molecularly imprinted polymer with 4-Aminoanyipyrine as template was prepared by precipitation polymerization.Methacrylic acid was used as functional monomer and dodecanol/toluene was used as solvent.The effects of reaction conditions,including the volume of solvent,the concentration of functional monomer and crosslinker,on the characteristics of the molecularly imprinted polymer were investigated.The appropriate polymerization conditions occurrs when the molecular ratio of template to monomer to crosslinker is 1∶5∶20.The obtained polymer shows good specific recognition and binding capacity in the rebinding experiments,with the separation factor of 3.72.福建省青年科技人才创新基金(2004J018);; 福建省自然科学基金(E0610030
