为探究低浓度污染物对环境和人类健康的危害,采用红细胞微核和核异常测试法研究了五种不同品牌、不同体积分数的洗发剂对泥鳅(Misgurnus anguillicaudatus)红细胞微核的影响。结果显示,洗发剂所诱导的泥鳅红细胞微核率在品牌与体积分数上均存在极显著差异(P<0.01),而且与两者之间的交互作用有关(P<0.01)。试验表明目前常用的洗发剂大多具有致突变活性,尤其飘柔、舒蕾两种洗发剂致突变活性更强。To investigate the harm of the pollution at low concentration to the environment and human being,the effects of five shampoos on micronuclei in erythrocytes of loach Misgurnus anguillicaudantus were studied by using micronuclei and nuclear anomalies tests.The loach was exposed in various concentrations of shampoos of 5 brands for 3 d respectively.Smears of blood samples were prepared.The results showed that each shampoo in various concentrations could all significantly increase the frequency of micronuclei respectively.There was statistically significant difference among shampoos at brand and concentration.And the micronuclei increased significantly with the interaction between the concentration and brand for shampoo-exposed individuals.The test indicated that most shampoos,especially Rejoice and Slek,had mutagenic activity.国家自然科学基金(40476040);; 福建省自然科学基金(D0410006
