In this paper, an improved dissipative particle dynamics (DPD) method was applied to simulate droplet motion in a grooved microchannel. Firstly the static contact angle between the droplet and the solid wall was simulated with the improved potential function, and "static contact angle~awf/af " curve was obtained by Polynomial Fit of the 2nd order. Then the influences of wall wettability, flow field force on the flow pattern of droplet were investigated
in a grooved microchannel. The results show that wall wettability and flow field force have large effects on the flow pattern of the droplet