Purpose: This study aims to discuss the difficulties faced by two large Brazilian industrial companies in technological innovation management. Design/methodology/approach: Initially, a literature review is carried out using meta-synthesis technique to consolidate an expanded and detailed framework that complemented and dialoged with the difficulties presented by Oslo Manual. The difficulties presented in this framework were used as an instrument to conduct two case studies. Findings: There were several findings, especially the adherence to the structured framework and the identification of short-term management and inflexibility of the regulatory environment as relevant difficulties for both companies. Originality/value: The understanding of these difficulties can contribute to optimizing manufacturers performance in innovation processes. Although only two companies were analyzed, their magnitude and relevance in the sectors they belong to should be highlighted. The information presented here can greatly contribute to expanding the debates about the management of innovation by companies in emerging countries
