Not AvailableBlood and hair samples were collected from seventy adult cattle reared in villages located near the industrial effluent contaminated River adjoining Meerut. Based on the distance of the villages from the river, they were divided into three areas viz. area 1 (villages located on the river bank), area 2 (villages within 1km distance from the river) and area 3 (villages more than 2 km from the river). Samples collected from cattle reared in rural locality away from the river were used as control. The mean lead (Pb) and cadmium (Cd) levels of blood and hair in the animals of area 1 and area 2 were significantly higher (P<0.05) as compared to control animals. The mean Pb and Cd levels of animals of area 3 were not significantly different from control values. Significantly low (P<0.05) copper and iron concentration in blood and hair were recorded in the animals from area1 and area 2 as compared to area 3 and control animals. Blood and hair zinc levels were not significantly different among animals of different areas. The blood cadmium level had significant negative correlation with blood copper(r=-0.379, p<0.01) and iron(r= -0.395, p<0.01). The blood lead levels had significant negative correlation with blood iron (r= -0.138, p< 0.05) and hair copper (r= -0.178, p< 0.05) and iron (r= -0.302, p< 0.05). The blood cadmium level had significant negative correlation with hair copper (r=-0.377, p< 0.01) and iron (r= -0.482, p<0.01). The study concludes that blood lead and cadmium influenced the concentration of trace minerals in the blood and hair.ICA