This supplementary material contains all inferential statistics for the published article " Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia"

Burden, Adrian

Morse, Christopher I.

Onambélé-Pearson, Gladys

Payton, Carl J.

Sims, David

E-space: Manchester Metropolitan University's Research Repository

Sims, David and Onambélé-Pearson, Gladys and Burden, Adrian and Pay-ton, Carl J. and Morse, Christopher I. (2018)Morphological and mechanicalproperties of the human patella tendon in adult males with Achondroplasia -Supplementary Material. [Dataset]Downloaded from: http://e-space.mmu.ac.uk/620683/Version: Full ArchivePublisher: Manchester Metropolitan UniversityUsage rights: ["licenses\_typename\_i" not defined]Please cite the published versionhttp://e-space.mmu.ac.ukSupplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.1df F Ratio P Value η2Within 9,216 35.724 < 0.001 93.7Between 1,24 63.171 < 0.001 72.5Interaction 9,216 62.946 < 0.001 72.4% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 8.9 (1.9) 25.4 (3.8) < 0.001 5.781 16.5 11.2 19.020 17.8 (3.9) 50.8 (7.5) < 0.001 5.781 33.0 22.3 38.030 26.7 (5.8) 76.2 (11.3) < 0.001 5.781 49.5 33.5 56.940 35.6 (7.7) 101.6 (15.1) < 0.001 5.781 65.9 44.6 75.950 44.6 (9.7) 127.0 (18.9) < 0.001 5.781 82.4 55.8 94.960 53.5 (11.6) 152.4 (22.6) < 0.001 5.781 98.9 66.9 113.970 62.4 (13.5) 177.8 (26.4) < 0.001 5.781 115.4 78.1 132.980 71.3 (15.4) 203.2 (30.2) < 0.001 5.781 131.9 89.2 151.890 80.2 (17.4) 227.9 (34.6) < 0.001 5.678 147.7 99.3 170.4100 92.8 (20.0) 260.1 (37.9) < 0.001 5.772 167.3 113.9 192.6Table 1a) Main effect statistics for torque production during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredTable 1b) Between group post hoc comparisons of torque production (N·m) of the knee extensors at 10% intervals of isometric maximal volentary contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Supplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.2df F Ratio P Value η2Within 9,216 102.091 < 0.001 81Between 1,24 32.948 < 0.001 57.9Interaction 9,216 2.65 < 0.001 9.9% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 38.3 (3.9) 52.4 (4.3) < 0.001 3.429 14.1 7.8 16.620 39.1 (3.8) 53.2 (4.8) < 0.001 3.289 14.1 7.5 16.830 39.5 (3.5) 54.1 (4.6) < 0.001 3.582 14.5 8.0 17.040 40.0 (3.6) 54.8 (4.8) < 0.001 3.534 14.8 8.1 17.550 40.5 (3.4) 55.4 (4.8) < 0.001 3.632 15.0 8.2 17.660 41.0 (3.5) 55.8 (4.9) < 0.001 3.557 14.8 8.3 17.770 41.6 (3.1) 56.1 (5.0) < 0.001 3.580 14.5 8.0 17.380 41.9 (3.3) 56.7 (5.1) < 0.001 3.541 14.7 8.0 17.590 42.1 (3.5) 57.4 (5.0) < 0.001 3.594 15.3 8.5 18.0100 42.5 (3.4) 58.4 (4.9) < 0.001 3.837 15.8 9.3 18.7Table 2b) Between group post hoc comparisons of patella tendon elongation (mm) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Table 2a) Main effect statistics for patella tendon elongation during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredSupplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.3df F Ratio P Value η2Within 9,216 397.064 < 0.001 94.3Between 1,24 71.85 < 0.001 75Interaction 9,216 71.081 < 0.001 74.8% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 241 (62) 677 (99) < 0.001 5.411 436 307 50420 482 (125) 1353 (197) < 0.001 5.411 871 614 100930 723 (187) 2030 (296) < 0.001 5.411 1307 921 151340 964 (250) 2707 (394) < 0.001 5.411 1743 1228 201750 1205 (312) 3384 (493) < 0.001 5.411 2178 1535 252160 1446 (375) 4060 (591) < 0.001 5.411 2614 1842 302670 1687 (437) 4737 (690) < 0.001 5.411 3050 2148 353080 1928 (500) 5414 (789) < 0.001 5.411 3485 2455 403490 2169 (562) 6071 (904) < 0.001 5.325 3902 2734 4526100 2511 (659) 6931 (1005) < 0.001 5.315 4420 3125 5123Table 3a) Main effect statistics for patella tendon elongation during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredTable 3b) Between group post hoc comparisons of patella tendon force (N) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Supplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.4df F Ratio P Value η2Within 9,216 89.676 < 0.001 78.9Between 1,24 0.376 0.545 1.5Interaction 9,216 0.564 0.826 2.3% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 3.3 (2.3) 2.7 (1.5) 0.612 0.311 31.1 -1.9 1.220 5.2 (3.5) 4.0 (2.5) 0.385 0.393 39.3 -3.5 1.430 6.3 (3.2) 5.6 (2.8) 0.550 0.242 24.2 -3.1 1.740 7.4 (3.2) 6.8 (3.0) 0.764 0.190 19.0 -3.0 2.250 8.5 (3.7) 7.9 (3.0) 0.740 0.191 19.1 -3.3 2.460 9.7 (3.4) 8.5 (3.3) 0.627 0.344 34.4 -3.5 2.270 11.0 (4.1) 9.0 (3.2) 0.299 0.570 57.0 -4.6 1.580 11.7 (3.9) 9.9 (3.3) 0.398 0.507 50.7 -4.3 1.890 12.0 (3.6) 11.0 (3.4) 0.588 0.298 29.8 -3.8 2.2100 13.0 (4.1) 12.6 (3.3) 0.934 0.114 11.4 -3.0 3.2Table 4a) Main effect statistics for patella tendon strain during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredTable 4b) Between group post hoc comparisons of patella tendon strain (%) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Supplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.5df F Ratio P Value η2Within 9,216 3433.253 < 0.001 93.5Between 1,24 43.808 < 0.001 64.6Interaction 9,216 43.982 < 0.001 64.7% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 2.8 (0.8) 6.3 (1.4) < 0.001 3.209 3.5 2.3 4.520 5.6 (1.5) 12.6 (2.8) < 0.001 3.209 7.0 4.7 8.930 8.5 (2.3) 18.9 (4.3) < 0.001 3.209 10.5 7.0 13.440 11.3 (3.0) 25.2 (5.7) < 0.001 3.209 14.0 9.3 17.950 14.1 (3.8) 31.5 (7.1) < 0.001 3.209 17.5 11.7 22.360 16.9 (4.5) 37.9 (8.5) < 0.001 3.209 20.9 14.0 26.870 19.7 (5.3) 44.2 (9.9) < 0.001 3.209 24.4 16.3 31.280 22.5 (6.0) 50.5 (11.4) < 0.001 3.209 27.9 18.7 35.790 25.4 (6.8) 56.6 (12.7) < 0.001 3.202 31.2 20.8 39.9100 29.4 (8.0) 64.5 (14.0) < 0.001 3.191 35.2 23.8 44.9Table 5b) Between group post hoc comparisons of patella tendon stress (MPa) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Table 5a) Main effect statistics for patella tendon stress during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredSupplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.6df F Ratio P Value η2Within 9,216 1134.06 < 0.001 97.9Between 1,24 106.768 < 0.001 81.6Interaction 9,216 52.333 < 0.001 68.6% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 271 (24) 668 (19) < 0.001 18.329 397 295 42720 354 (37) 786 (32) < 0.001 12.434 432 321 47030 420 (47) 888 (43) < 0.001 10.411 467 346 51240 478 (55) 979 (51) < 0.001 9.384 502 371 55250 529 (63) 1063 (59) < 0.001 8.762 534 394 59060 576 (69) 1141 (66) < 0.001 8.349 565 416 62670 619 (75) 1213 (73) < 0.001 8.053 594 437 66080 659 (80) 1281 (79) < 0.001 7.810 623 457 69390 697 (86) 1345 (86) < 0.001 7.548 648 474 723100 748 (93) 1418 (101) < 0.001 6.890 670 486 753Table 6a) Main effect statistics for patella tendon stiffness during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredTable 6b) Between group post hoc comparisons of patella tendon stiffness (N·mm-1) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Supplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.7df F Ratio P Value η2Within 9,216 487.7 < 0.001 95.1Between 1,24 74.21 < 0.001 74.8Interaction 9,216 37.136 < 0.001 59.8% Max Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI Upp10 0.12 (0.03) 0.32 (0.05) < 0.001 4.756 0.20 0.16 0.2420 0.17 (0.04) 0.39 (0.07) < 0.001 4.049 0.22 0.17 0.2730 0.20 (0.05) 0.45 (0.08) < 0.001 3.877 0.25 0.19 0.3040 0.23 (0.06) 0.50 (0.09) < 0.001 3.718 0.27 0.20 0.3350 0.26 (0.06) 0.55 (0.10) < 0.001 3.648 0.29 0.22 0.3660 0.28 (0.07) 0.59 (0.10) < 0.001 3.540 0.31 0.23 0.3970 0.31 (0.07) 0.63 (0.11) < 0.001 3.487 0.32 0.24 0.4180 0.33 (0.08) 0.67 (0.12) < 0.001 3.472 0.34 0.26 0.4390 0.35 (0.08) 0.72 (0.12) < 0.001 3.529 0.37 0.28 0.46100 0.38 (0.09) 0.77 (0.14) < 0.001 3.465 0.39 0.29 0.49Table 7a) Main effect statistics for patella tendon Young's Modulus during isometric volentary contraction of the knee extensors in adult males with Achondroplasia and controls.df, Degrees of Freedom; η2, Partial eta squaredTable 7b) Between group post hoc comparisons of patella tendon Young's Modulus (GPa) at 10% intervals of isometric maximal volentary knee extensor contraction in Achondroplasic males and controls. Values given as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Supplementary data for the following publication: Sims et al. (2018) 'Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia.' Frontiers in Physiology.8Achondroplasia Control P Value Effect Size Mean Diff. 95% CI Low 95% CI UppPennation at Rest 15.6 (3.2) 13.8 (2.4) 0.105 0.645 1.801 -0.402 4.005Pennation at iMVC 20.9 (4.6) 17.4 (2.4) 0.012 1.013 3.541 0.839 6.243Fibre Length at Rest 9.5 (2.4) 10.5 (1.5) 0.199 0.495 0.969 -0.542 2.479Fibre Length at iMVC 6.8 (1.5) 8.2 (1.5) 0.029 0.926 1.408 0.16 2.656Pennation Rest Pennation MVC P Value Effect Size Mean Diff. 95% CI Low 95% CI UppAchondroplasia 15.6 (3.2) 20.9 (4.6) < 0.001 1.361 3.55 2.236 4.864Control 13.8 (2.4) 17.4 (2.4) < 0.001 1.467 5.29 3.527 7.053Fibre Length Rest Fibre Length MVC P Value Effect Size Mean Diff. 95% CI Low 95% CI UppAchondroplasia 9.5 (2.4) 6.8 (1.5) < 0.001 1.367 2.7 1.72 3.68Control 10.5 (1.5) 8.2 (1.5) < 0.001 1.489 2.261 1.531 2.991Table 8b) Within group post hoc comparisons of vastus lateralis pennation angle (°) from rest to isometric volentary contraction in adult males with Achondroplasia and controls. Values displayed as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Table 8c) Within group post hoc comparisons of vastus lateralis fibre length (cm) from rest to isometric volentary contraction in adult males with Achondroplasia and controls. Values displayed as mean (SD).Mean Diff., Mean Difference; CI, Confidence Interval of the Mean Difference.Table 8a) Between group post hoc comparisons of vastus lateralis pennation angle (°) and fibre length (cm) from rest to isometric volentary contraction in adult males with Achondroplasia and controls. Values displayed as mean (SD).iMVC, isometric Maximal Volentary Contraction; CI, Confidence Interval of the Mean Difference

Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia - Supplementary Material

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Morphological and mechanical properties of the human patella tendon in adult males with Achondroplasia - Supplementary Material

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