In the present paper, the characterizations of regional gradient strategic sensors notions have been given for different cases of regional gradient observability. The results obtained are applied to two dimensional linear infinite distributed system in Hilbert space where the dynamic is governed by strongly continuous semi-group. Various cases of regional strategic sensors are considered and analyzed in connection with regional gradient strategic sensors concepts. Also, we show that there is a various sensors which are not gradient strategic in usual sense for the considered systems, but may be regionally gradient strategic of this system