The CERN-Neutrinos–to–Gran Sasso project (CNGS) is devoted to prove unambiguously the νμ → ντ oscillation channel in the atmospheric sector. The high-energy and high-intensity CNGS muon neutrino beam, generated at CERN, is directed towards the Italian Gran Sasso National Laboratory (LNGS), where the OPERA long-baseline experiment searches for ντ appearance. In this paper, a review of the performance and physics potential of the experiment together with the description of dedicated strategies to observe events with decay topologies in the OPERA target will be given