Technoeconomic and life-cycle analyses are presented for catalytic conversion of ethanol to fungible hydrocarbon fuel blendstocks, informed by advances in catalyst and process development. Whereas prior work toward this end focused on 3-step processes featuring dehydration, oligomerization, and hydrogenation, the consolidated alcohol dehydration and oligomerization (CADO) approach described here results in 1-step conversion of wet ethanol vapor (40 wt% in water) to hydrocarbons and water over a metal-modified zeolite catalyst. A development project increased liquid hydrocarbon yields from 36% of theoretical to >80%, reduced catalyst cost by an order of magnitude, scaled up the process by 300-fold, and reduced projected costs of ethanol conversion 12-fold. Current CADO products conform most closely to gasoline blendstocks, but can be blended with jet fuel at low levels today, and could potentially be blended at higher levels in the future. Operating plus annualized capital costs for conversion of wet ethanol to fungible blendstocks are estimated at 2.00/GJforCADOtodayand1.44/GJ in the future, similar to the unit energy cost of producing anhydrous ethanol from wet ethanol (1.46/GJ).Includingthecostofethanolfromeithercornorfuturecellulosicbiomassbutnotproductionincentives,projectedminimumsellingpricesforfungibleblendstocksproducedviaCADOarecompetitivewithconventionaljetfuelwhenoilis100 per barrel but not at 60perbarrel.However,withexistingproductionincentives,theprojectedminimumblendstocksellingpriceiscompetitivewithoilat60 per barrel. Life-cycle greenhouse gas emission reductions for CADO-derived hydrocarbon blendstocks closely follow those for the ethanol feedstock