This thesis is concerned with the application and
development of serum enzyme tests in the diagnosis of myocardial infarction. Two aspects of the problem have been
selected for detailed study: firstly, the measurement of
the activity of the MB isoenzyme of creatine kinase and,
secondly, the release of mitochondrial enzymes in myocardial infarction. In addition, the biochemical properties of the MB isoenzyme have been compared with those
of the MM isoenzyme of creatine kinase in an attempt to
provide the basis of a simple test for the measurement of
serum levels of the MB isoenzyme
