Primary non-gonococcal urethritis

Abstract

A study of the aetiology and diagnosis in males based on a series of 118 cases.There are two types of non -gonococcal urethritis, namely, primary and secondary.Primary non-gonococcal urethritis may be described as a urethritis arising independently of any gonococcal infection.Synonymous terms are primary non -gonorrhoeal urethritis, primary non -specific urethritis, urethritis simplex, idiopathic urethritis, and pseudo -gonorrhoea. The latter term is chiefly used .to describe the more acute cases of primary non - specific urethritis.Secondary non -gonococcal urethritis is a residual urethritis after the original infecting organism, the gonococcus, has apparently died out. This is a relatively frequent type as in the majority of cases of gonorrhoea, even within a few days of the appearance of the discharge, secondary organisms may be found in the purulent exudate. In 1930 the 'writer investigated a series of 155 cases of early acute gonorrhoea attending the Venereal Diseases Department of the Royal Infirmary, Edinburgh and cultured secondary organisms from the urethral pus of 130 patients (83.5 per cent). By far the commonest organism found was staphylococcus albus followed by diphtheroids, streptococci, staphylococcus aureus, and bacillus coli in that order of frequency.In the majority of cases, then, gonorrhoea is a ;mixed infection from the earliest stages of the -4- disease. A probable explanation of this phenomenon is that the organisms normally inhabiting, the anterior urethra become virulent, and as the disease spreads backwards to the posterior urethra these potential pathogens travel with it.Frequently secondary organisms gain a firm foothold in the damaged mucous membrane and may result in a continuance of the urethritis for a considerable period after the gonococci have been eliminated

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