This paper presents the fully integrated hardware-accelerated query engine for large-scale datasets in the context of Semantic Web databases. As queries are typically unknown at design time, a static approach is not feasible and not flexible to cover a wide range of queries at system runtime. Therefore, we introduce a runtime reconfigurable accelerator based on a Field Programmable Gate Array (FPGA), which transparently incorporates with the freely available Semantic Web database LUPOSDATE. At system runtime, the proposed approach dynamically generates an optimized hardware accelerator in terms of an FPGA configuration for each individual query and transparently retrieves the query result to be displayed to the user. During hardware-accelerated execution the host supplies triple data to the FPGA and retrieves the results from the FPGA via PCIe interface. The benefits and limitations are evaluated on large-scale synthetic datasets with up to 260 million triples as well as the widely known Billion Triples Challenge
