Uniformity of particles from laminar jet break-up

Abstract

Many applications such as particulate drug delivery for targeting or controlled release require particles to be uniform in size. Much of the recent attention has been attracted to the production of particle with a narrow particle distribution. Laminar jet break-up represents one of the easiest methods for production of uniformly-sized particles from liquid feeds. However, while it is generally acknowledged that particles produced by laminar jet break-up do have a relatively narrow particle size distribution, no quantitative results seem to appear in the open literature on the size distribution in relation to the operating conditions. This paper attempts to quantify the influences of material properties and process variables on the particle size distribution from a laminar jet break-up process

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