Aziz, I.

Brien, D.O.

George, H.A.

Hossain, M.Y.

Kurien, M.

Marks, L.J.S.

Richardson, J.I.

Rigby, R.

Sanders, D.S.

Trott, N.

M Kurien

I Aziz

N Trott

DO Brien

HA George

MY Hossain

LJS Marks

JI Richardson

R Rigby

DS Sanders

Crossref

PTU-135 How Much Gluten is the General Population Consuming and Does It Relate to Symptoms?

White Rose Research Online

This is a repository copy of How Much Gluten Is The General Population Consuming and Does It Relate to Symptoms?.White Rose Research Online URL for this paper:http://eprints.whiterose.ac.uk/113911/Version: Accepted VersionProceedings Paper:Kurien, M., Aziz, I., Trott, N. et al. (7 more authors) (2016) How Much Gluten Is The General Population Consuming and Does It Relate to Symptoms? In: GUT. BSG 2016, 20 - 23 June, 2016, Liverpool, UK. http://doi.org/10.1136/gutjnl-2016-312388.221, 65 . BMJ Publishing Group , A124-A124. https://doi.org/10.1136/gutjnl-2016-312388.221eprints@whiterose.ac.ukhttps://eprints.whiterose.ac.uk/Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, Designs and Patents Act 1988 allows the making of a single copy solely for the purpose of non-commercial research or private study within the limits of fair dealing. The publisher or other rights-holder may allow further reproduction and re-use of this version - refer to the White Rose Research Online record for this item. Where records identify the publisher as the copyright holder, users can verify any specific terms of use on the publisher’s website. Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing eprints@whiterose.ac.uk including the URL of the record and the reason for the withdrawal request. BSG 2016 - Abstract SubmissionNeurogastroenterology: functional disorders, motility and clinical physiologyBSG16-ABS-1128HOW MUCH GLUTEN IS THE GENERAL POPULATION CONSUMING AND DOES IT RELATE TO SYMPTOMS?M. Kurien* 1, I. Aziz1, N. Trott1, D. O. Brien1, H. A. George1, M. Y. Hossain1, L. J. S. Marks1, J. I. Richardson1, R. Rigby1,D. S. Sanders11Academic Unit of Gastroenterology, ROYAL HALLAMSHIRE HOSPITAL, Sheffield, United KingdomDoes this abstract contain original data?: YesWill this abstract be published/presented prior to June 2016?: NoThis abstract is: None of the aboveDoes your Endoscopy abstract include a video?: NoPreferred presentation type: Oral or PosterIntroduction: Gluten is a ubiquitous part of a western diet. It is implicated for causing an array of disorders, which haveboth intestinal and/or extraintestinal manifestations. Our understanding of this heterogeneous group of gluten-relateddisorders is advancing, however uncertainty exists as to how much gluten the general population is consuming. Thisstudy aims to address this knowledge gap and also assess the prevalence of self-reported gluten sensitivity within thegeneral population.Methods: Between September and October 2015 a population-based survey was undertaken in Sheffield, UK. Membersof the general public, all over the age of 16 years, were invited to complete a modified version of a previously validatedwritten questionnaire. This questionnaire assessed demographic information, GI conditions and also determined thepresence of gluten sensitivity (GS). In addition, total gluten consumption was calculated using a food frequencyquestionnaire. Participants were asked about their use of a gluten free diet (GFD), and whether they had seen ahealthcare professional for their symptoms. A diagnosis of coeliac disease (CD) was determined if individuals had adoctor diagnosis of CD, and were also taking a GFD. Results: 1003 adults completed the population-based survey (59% female, median age 31 years (16-86years). Themean consumption of gluten per day for this group was 13.2g (s.d=9.2g).  The self-reported prevalence of GS was 32.5%(326/1003, female 70% [P < 0.0001], age range 17椴82, median age 35yrs), with 3.7% (38/1003) on a GFD and 1.1%(12/1003) having CD. The proportion of GS individuals who had seen a doctor for their symptoms was 18.3% (65/326).Individuals with GS had an increased prevalence of fulfilling the Rome III criteria for irritable bowel syndrome, incomparison with those without GS (31.3% vs. 5.61%, odds ratio 7.66, p < 0.0001). In addition, mean daily consumption ofgluten was considerably lower in this GS group compared to the non GS group (10.8g vs. 14.4g, p<0.0001).Conclusion: This is the first study assessing gluten consumption in a UK population. Findings from our work highlight thatsensitivity to gluten-based products is common, and that affected individuals have a higher prevalence of IBS. Althoughonly a minority of individuals maintained a gluten-free diet, individuals with gluten related symptoms evidently wereelecting to reduce their gluten consumption. Disclosure of Interest: None Declared