BM CDT Research Proposals 2018/19 from GDC BIR. Title: Stereoselective, scalable route towards phosphorothioate analogues of ATP

Abstract

Enantioselective synthesis of phosphorothioate analogues of adenosine 5'-triphosphate is difficult to achieve in highly atom and cost-efficient way.1 Novel ideas to address this challenge are sought after, which could lead to a scalable and sustainable route towards analogues of (Sp)-ATP-αS