Chan, W.L

Liew , C.K

Liew, H.B

Ong, T.K

Piaw, C.S

Rapaee, A.

Samion, H.

Sim, K.H

Unimas Institutional Repository

Use of Non-Invasive Phase Contrast Magnetic Resonance Imaging for Estimation of Atrial Septal Defect Size and Morphology: A Comparison with Transesophageal Echo  Chin Sze Piaw, Ong Tiong Kiam, Annuar Rapaee, Liew Chee Khoon, Liew Houng Bang, Chan Wei Ling, Hasri Samion and Sim Kui Hian Abstract  Background:  Transesophageal echocardiography (TEE) is a trusted method of sizing atrial septal defect (ASD) prior to percutaneous closure but is invasive, uncomfortable, and may carry a small risk of morbidity and mortality. Magnetic resonance imaging (MRI) may be useful non-invasive alternative in such patients who refuse or are unable to tolerate TEE and may provide additional information on the shape of the A0SD.  Purpose:  To validate the accuracy of ASD sizing by MRI compared with TEE.  Method:  Twelve patients (mean age 30 years; range 11–60 years) scheduled for ASD closure underwent TEE, cine balanced fast field echo MRI (bFFE-MRI) in four-chamber and sagittal views and phase-contrast MRI (PC-MRI) with reconstruction using the two orthogonal planes of T2-weighted images as planning. The average of the three longest measurements for all imaging modalities was calculated for each patient.  Results:  Mean maximum ASD length on TEE was 18.8 ± 4.6 mm, mean length by bFFE-MRI was 20.0 ± 5.0 mm, and mean length by PC-MRI was 18.3 ± 3.6 mm. The TEE measurement was significantly correlated with the bFFE-MRI and PC-MRI measurements (Pearson r = 0.69, p = 0.02 and r = 0.59, p = 0.04, respectively). The mean difference between TEE and bFFE-MRI measurements was −1.2mm (95% CI: −3.7, 1.3) and between TEE and PC-MRI was 0.5 mm (95% CI: −1.9, 2.9). Bland–Altman analysis also determined general agreement between both MRI methods and TEE. The ASDs were egg-shaped in two cases, circular in 1 patient and oval in the remaining patients.  Conclusion:  ASD sizing by MRI using bFFE and phase-contrast protocols correlated well with TEE estimations. PC-MRI provided additional information on ASD shapes and proximity to adjacent structures.  Keywords  ASD - MRI - Phase - contrast imaging - TEE   Published in CardioVascular and Interventional Radiology, Volume 29, Number 2, 230-234, 2006. 

Use of Non-Invasive Phase Contrast Magnetic Resonance Imaging for Estimation of Atrial Septal Defect Size and Morphology: a comparison with transesophageal Echo.

http://ir.unimas.my/id/eprint/2499/1/Use%20of%20Non-Invasive%20Phase%20Contrast%20Magnetic%20Resonance%20Imaging%20for%20Estimation%20of%20Atrial%20Septal%20Defect%20Size%20and%20Morphology%20a%20comparison%20with%20transesophageal%20Echo..pdf

Use of Non-Invasive Phase Contrast Magnetic Resonance Imaging for Estimation of Atrial Septal Defect Size and Morphology: a comparison with transesophageal Echo.

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