Lack of effective tools to diagnose lung cancer at
an early stage has caused high mortality in cancer patients
especially in lung cancer patients. Electronic nose (E-Nose)
technology is believed to offer non-invasive, rapid and reliable
analytic approach by measuring the odour released from
cancer to assist medical diagnosis. In this work, using a
commercial E-nose (Cyranose-320), we aimed to detect the
volatile organic compounds (VOCs) emitted by different types
of cancerous cells. The lung cancer cell (A549) and breast
cancer cell (MCF-7) were used for this study. Both cells were
cultured using Dulbecco’s Modified Eagle’s Medium (DMEM)
with 10% of Fetal Bovine Serum (FBS) and incubated for three
days. The static headspace of cell cultures and blank medium
were directly sniffed by Cyranose-320. The preliminary results
from this study showed that, the E-nose is able to detect and
distinguish the presence of VOCs in cancerous cells with
accuracy of 100% using LDA. To this end, the VOCs emitted
from cancerous cells can potentially used as biomarker
