Elevated levels of naturally occurring autoantibodies to human chorionic gonadotropin (hCG) β core fragment in a female patient with thyroid follicular adenoma: Case report

Abstract

We report a case of a woman, who had an elevated levels of naturally-occurring autoantibodies to human chorionic gonadotropin (hCG) β core fragment (hCGβcf) one year prior to the development of thyroid follicular lesion. The patient underwent surgery and the histology report demonstrated that the lesion was a follicular adenoma. Further investigations of the role of naturally-occurring autoantibodies (NAAbs) to anti-hCGβcf in the pathogenesis of varioustumours of thyroid gland might be useful in the development of novel diagnostic methods, using anti-hCGβcf NAAbs as a marker for the detection of unsuspected thyroid tumour