학위논문 (석사)-- 서울대학교 대학원 : 의학과 영상의학 전공, 2016. 2. 홍성환.Purpose: To investigate the effect of fat suppression on T2 mapping of the articular cartilage in porcine knee joint at MR imaging.
Materials and Methods: Eleven porcine knee joints were harvested en bloc with intact capsules and surrounding muscles. We performed T2 mapping of articular cartilage in the medial femoral condyle with (FST2) and without (cT2) fat suppression in sagittal plane with two frequency encoding directions: from superior to inferior (SI) and from inferior to superior (IS). Consequently, four types of T2 map were obtained: FST2-SI, FST2-IS, cT2-SI and cT2-IS. Two observers measured T2 values of the medial femoral condyle cartilage at four regions including anterior oblique, central horizontal, posterior oblique and posterior vertical portions.
Results: There was no significant difference of mean T2 values between FST2-SI and FST2-IS at all regions (p = 0.165, 0.873, 0.077, 0.483, respectively). Mean T2 values of cT2-SI were, however, significantly lower than those of cT2-IS at three regions (p = 0.057, 0.033, <0.001, 0.019, respectively). Coefficient of variation (CV) values between two FST2 maps were lower than those between two cT2 maps in all four regions (17.91-25.57 vs. 25.51-78.72). In addition, ICC between two FST2 maps was higher than that between two cT2 maps (0.276-0.800 vs -0.032-0.455) at three regions except the central horizontal region.
Conclusion: Frequency encoding direction greatly affects T2 values of the articular cartilage in conventional T2 mapping. In comparison with conventional T2 mapping, fat-suppressed T2 mapping provides more reproducible T2 values of the articular cartilage by eliminating chemical shift artifact.Introduction 1
Materials and Methods 2
Results 5
Discussion 7
Reference 11
Abstract in Korean 23Maste
