The potential for thorium as an alternative or supplement to uranium in fission power generation has long been recognised, and several reactors, of various types, have already operated using thorium-based fuels. Accelerator Driven Subcritical (ADS) systems have benefits and drawbacks when compared to conventional critical thorium reactors, for both solid and molten salt fuels. None of the four options – liquid or solid, with or without an accelerator – can yet be rated as better or worse than the other three, given today's knowledge. We outline the research that will be necessary to lead to an informed choice