Alstonoside, a secoiridoid glucoside from Alstonia scholaris

Abstract

1298-1302From the stems of Alstonia scholaris, a new secoiridoid glucoside, named alstonoside 1, together with two isoflavone apioglucosides, formononetin 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside 2 and biochanin A 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside 3 are isolated and their structures are elucidated on the basis of detailed 1D and 2D-NMR and mass spectral data. Alstonoside features the presence of a ring opened monocyclic iridoid glucoside with the presence of an O-benzoyl moiety. This study constitutes the first report of a new secoiridoid glucoside and two isoflavone apioglucosides from this plant