Blood Pressure and White-Matter Disease Progression in a Biethnic Cohort: Atherosclerosis Risk in Communities (ARIC) Study

Abstract

Blood pressure (BP) is a predictor of concurrent and subsequently measured white matter hyperintensity (WMH), but longitudinal studies of WMH change and data in black participants are lacking. We hypothesized that WMH progression would be 1) strongly related to BP in blacks and whites, and 2) predicted more strongly by earlier (midlife) or cumulative BP measurements than by measures at older ages

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