Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

Altshuler, David; Aspelund, Thor; Bielak, Lawrence F.; Bis, Joshua C.; Blankenberg, Stefan; Boerwinkle, Eric; Borecki, Ingrid B.; Cunningham, Julie; Cupples, L. Adrienne; de Andrade, Mariza; Dehghan, Abbas; Eiriksdottir, Gudny; Elias-Smale, Suzette E.; Elosua, Roberto; Feitosa, Mary F.; Fox, Caroline S.; Glazer, Nicole L.; Gudnason, Vilmundur; Harris, Tamara B.; Heiss, Gerardo; Herrington, David M.; Hoffmann, Udo; Hofman, Albert; Howard, Timothy D.; Hwang, Shih-Jen; Johnson, Andrew D.; Kardia, Sharon L.R.; Kathiresan, Sekar; Kavousi, Maryam; Kraja, Aldi T.; Krestin, Gabriel P.; Launer, Lenore J.; Liu, Yongmei; Massaro, Joseph M.; Mitchell, Braxton D.; Murabito, Joanne M.; Münzel, Thomas F.; Nalls, Michael; Newman, Ann B.; Oudkerk, Matthijs; O’Connell, Jeffrey R.; O’Donnell, Christopher J.; Peyser, Patricia A.; Post, Wendy; Province, Michael A.; Psaty, Bruce M.; Rotter, Jerome I.; Salomaa, Veikko; Schillert, Arne; Schnabel, Renate B.; Schwartz, Stephen M.; Shen, Haiqing; Shuldiner, Alan R.; Sigurdsson, Sigurdur; Siscovick, David S.; Smith, Albert V.; Sun, Yan V.; Uitterlinden, Andre G.; van der Lugt, Aad; van Duijn, Cornelia M.; Voight, Benjamin F.; White, Charles C.; Wild, Philipp S.; Witteman, Jacqueline C.; Zeller, Tanja; Zhang, Qunyuan; Ziegler, Andreas

Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction

Authors: David Altshuler
Thor Aspelund
Lawrence F. Bielak
Joshua C. Bis
Stefan Blankenberg
Eric Boerwinkle
Ingrid B. Borecki
Julie Cunningham
L. Adrienne Cupples
Mariza de Andrade
Abbas Dehghan
Gudny Eiriksdottir
Suzette E. Elias-Smale
Roberto Elosua
Mary F. Feitosa
Caroline S. Fox
Nicole L. Glazer
Vilmundur Gudnason
Tamara B. Harris
Gerardo Heiss
David M. Herrington
Udo Hoffmann
Albert Hofman
Timothy D. Howard
Shih-Jen Hwang
Andrew D. Johnson
Sharon L.R. Kardia
Sekar Kathiresan
Maryam Kavousi
Aldi T. Kraja
Gabriel P. Krestin
Lenore J. Launer
Yongmei Liu
Joseph M. Massaro
Braxton D. Mitchell
Joanne M. Murabito
Thomas F. Münzel
Michael Nalls
Ann B. Newman
Matthijs Oudkerk
Jeffrey R. O’Connell
Christopher J. O’Donnell
Patricia A. Peyser
Wendy Post
Michael A. Province
Bruce M. Psaty
Jerome I. Rotter
Veikko Salomaa
Arne Schillert
Renate B. Schnabel
Stephen M. Schwartz
Haiqing Shen
Alan R. Shuldiner
Sigurdur Sigurdsson
David S. Siscovick
Albert V. Smith
Yan V. Sun
Andre G. Uitterlinden
Aad van der Lugt
Cornelia M. van Duijn
Benjamin F. Voight
Charles C. White
Philipp S. Wild
Jacqueline C. Witteman
Tanja Zeller
Qunyuan Zhang
Andreas Ziegler
Publication date: 1 January 2011
Publisher
Doi

Abstract

Coronary artery calcification (CAC) detected by computed tomography is a non-invasive measure of coronary atherosclerosis, that underlies most cases of myocardial infarction (MI). We aimed to identify common genetic variants associated with CAC and further investigate their associations with MI

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