Psychometric Evaluation of Patient-Reported Outcomes in Irritable Bowel Syndrome Randomized Controlled Trials: A Rome Foundation Report

Abstract

There is debate about how best to measure patient reported outcomes (PROs) in irritable bowel syndrome (IBS). We pooled data from clinical trials to measure the psychometric properties of IBS endpoints, including binary responses (e.g. “adequate relief”) and 50% improvement in symptom severity