This study aims to determine the influence of Eimeria magna (E. magna) on the physiological condition of
local rabbits. Twelve of local coccidiosis free, male rabbits aged 4 months, 1.0 to 1.5 kg body weight, were used as experiment animals. The rabbits were randomly divided into 3 groups (K-O, K- I, and K-2), each group
consisted of4 rabbits. Each rabbit of group K-l and K-2 was infected orally with 4xlOs/ rabbit and 28x10s/ ofE.
magna oocysts, respectively. The rabbits of the group K-O were used as a control. The measurement of body
temperature, feed consumed weighing and counting the number of eliminated Eimeria were carried out in feces
and monitoring of clinical symptoms was done every day for I I days. On day-O, 5, and 10 the body weight were measured and blood for routine blood tests (number of erythrocytes, leucocytes, hemoglobin level, the value of packed cell volume (PCY), total levels of plasma protein (TPP), and differential leucocyte (neutrophils, eosinophils, basophils, monocytes and lymphocytes) was collected. The results showed that rabbits infected with 28xlOs oocyst exhibit in physiological conditions more effectively than those of the group infected with 4xlOs/ oocyst.. The higher the number oocyst E . magna administered, the higher the body temperature, the amount oocyst eliminated in feces, and the number eosinophils