Alzheimer disease or Alzheimer type of senile dementia is a nomenclature which widely used by neurologist Dr Alois Alzheimer is the first person who introduced signs of progressive dementia disorder in female patient. In early phase, the first sign is memory disturbances, delayed and inadequate respons. With special methods, Katzmann and Terry arranging consensus diagnosing Alzheimer disease. There are no specific additional investigation, CT scan only provide measurement of NINCDS-ADRDA Work Group providing diagnostic criteria for Alzheimer dementia. Management of patient needs to approve especially for behaviour disorder, effective care by families and appropriate treatments.
Key words: Alzheimer\u27s disease - dementia - senile dementia - physostigmine - nerve growth facto