Vaksinasi monovalen dan polivalen vaksin untuk mengatasi serangan Aeromonas hydrophila pada ikan lele (Clarias sp.). (Monovalent And Polyvalent Vaccination On Walking Catfish (Clarias sp.) Against Aeromonas hydrophila).

Abstract

Aeromonas hidrophila is an opportunistic pathogen that has always caused high mortality in catfish farming. The use of medication is not significantly effective to control the disease. On the other hand medication can cause pollution and increase the number of resistant strains of bacteria to the drugs. The use of vaccination seems promising in controlling the disease. However the problem is that A. hydrophila has antigenic heterogenicity. The objectives of the study were to the eficacy of monovalent and polyvalent vaccines various methods of vaccination (oral, waterborne and i.m inâ¢jection), in various ages of cat fish fingerlings, in passive vaccination, and the pro⢠duction of antibody of vaccinated fish. tsi The result showed that the eficacy of polyvalent vaccine was higher than monovalent vaccine especially in i.m injection. In general i.m inject ion was more effective than oral and waterborne vaccinations. Passive vaccination could elevate the resistency of catfish fry until about 50 days after hatching. The mortality of fry from vaccinated breeder was significantly higher than the mortality of from unvaccinated breeder. By waterborne infection the mortality of fry from vaccinated breeder on 21, 35 and 50 days after hatching were 3.3%, 0% and 24.17%. While the fry froM unvaccinated breeder were 95.0%, 60.0% and 35,0%. The antibody of vaccinated fish was still detected until 12 weeks after vaccination

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