The Stereotchemistry Effect of Eugenol, C/S-Isoeugenol and Trans-Isoeugenol on Their Catalytic Hidrogenation = Pengaruh Stereokimia Molekul Eugenol, cis-Isoeugenol, dan trans-Isoeugenol Pada Reaksi Hidrogenasi Katalitik.

Abstract

The stereochemistry effect of eugenol, cis-isoeugenol and trans-isoeugenol on their catalytic hydrogenation by Ni/y-Al203 catalyst was investigated. In this investigation, the catalyst is prepared by impregnation of Nickel into solid of y-Al203 in methanol as a solvent. The calcination process, which is followed by reduction, is performed on Muchalal reactor at 400 °C. After that, the catalytic hydrogenation is carried out under hydrogen gas atmosphere by mixing 10 mL sample and 0.5 g Ni/y-Al203 catalyst at 200°C for 3 hours. The stereochemistry effect of reactants is evaluated by computer modelling using PM3 semiempirical methods. The mass spectrum of catalytic hydrogenation product from those compounds shows a molecular ion at Ink 164, which proves the existence of 2 âmethoxy-4-propylphenol. The eugenol gives the highest conversion (99%), followed by cis-isoeugenol (81%) and trans-isoeugenol (67%). It was found that there is a correlation between the stereochemistry of those compounds and catalytic reactivity. Keywords: stereochemistry effects, 2-methoxy-4-propylpheno