<span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">Synthesis and fungicidal activity of some 8-aryl-3-(<span style="font-size:10.0pt;font-family:Symbol; mso-ascii-font-family:"Times New Roman";mso-fareast-font-family:"Times New Roman"; mso-hansi-font-family:"Times New Roman";mso-bidi-font-family:Mangal;mso-ansi-language: EN-US;mso-fareast-language:EN-US;mso-bidi-language:HI;mso-char-type:symbol; mso-symbol-font-family:Symbol" lang="EN-US"><img src='/image/spc_char/beta.gif' border=0><span style="font-size:10.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-US;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-US">-D-glucopyranosyl)-4-oxo-4<i style="mso-bidi-font-style:normal">H</i>,5<i style="mso-bidi-font-style:normal">H</i>-1,2,4-triazolo-[4,3-<i style="mso-bidi-font-style:normal">b</i>]-1,4,2,6-dithiadiazine-1,1-dioxides</span></span></span>

Abstract

682-6868-Aryl-3-(-D-<span style="mso-bidi-font-weight: bold">glucopyranosyl)-4-oxo-4H,5H-1,2,4-triazolo-[4,3-<i style="mso-bidi-font-style: normal">b]-1,4,2,6-dithiadiazine-1,1-dioxides <b style="mso-bidi-font-weight: normal">4<span style="mso-bidi-font-weight: bold" lang="EN-US"> have been conveniently prepared from 8-aryl-4-oxo-4<i style="mso-bidi-font-style: normal">H,5H-1,2,4-triazolo-[4,3-b]-1,4,2,6-dithiadiazine-1,1-dioxides 2 by reaction of β-d-1,2,3,4,6-penta-O-acetylglucopyranose and iodine. Compounds 2 are synthesized by reported methods from 3-mercapto-5-aryl-1,2,4-triazole 1, chlorosulphonyl isocyanate and N-di-isopropyl-ethylamine in acetonitrile. All compounds have been tested in vitro for their antifungal activity against three fungal species Cephalosporium saccharii, Colletotrichum falcatum and Helminthosporium oryzae. </span