Microwave induced eco-friendly solvent-free synthesis of 6-arylquinazolino[3,2-α] [1,8]naphthyridin-13-ones

Abstract

1584-1586An efficient and rapid method for the synthesis of 6-arylquinazolino[3<span style="color:#121212;mso-bidi-language: HI">,2-α] [1,8]naphthyridin-13-ones 3 by the reaction of 3-aryl-2-chloro-1,8-naphthyridines 1 with anthranilic acid 2 in the presence of catalytic amount of DMF in solvent-free conditions under microwave irradiation is reported. The products are obtained in very good yields and in a state of high purity<span style="color:#3A3A3A; mso-bidi-language:HI">. </span