An investigatory study of antibacterial activity of functionalized spirooxindoles

Abstract

399-411Synthesis of functionalized spirooxindoles have been reviewed and it has been proposed that the unique core ring system that is common to this family of compounds arises by a biological Knoevengal-Michael-Domino cyclization along with the attachment of hydrophobic alkyl chain linkage. These newly synthesized compounds have been also tested for their in vitro antibacterial activities against some bacterial strains <i style="mso-bidi-font-style: normal">viz. Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa. </i