Synthesis of some new 3-cummamoyl counarin oximes and related cyclisation products derived from 3-acetyl coumarin

Abstract

1223-1225<span style="font-size: 12.0pt;font-family:" times="" new="" roman";mso-bidi-language:ar-sa"="">3-Acetylcoumarin 1 reacts with aldehydes to form corresponding 3-cummamoyl counarin 2a-g. Oximation of 2a-g with hydroxylamine hydrochloride in ethanol and (or) isopropanol <span style="font-size: 12.0pt;font-family:" times="" new="" roman";mso-bidi-language:ar-sa"="">aqueous solution give new 3-[1-oxo-3-(substituted-phenyl)]- 2- propenyl-2<i style="mso-bidi-font-style: normal">H-1-benzopyran-2-one- oximes 3a-e and 5-substituted- 3-(2H-1-benzopyran-2-one-3-yl)-4, 5-dihydro-isoxazoles 4f-g. </span