<i><span style="font-size:21.5pt;mso-bidi-font-size:13.5pt;font-family:"Times New Roman","serif"">In vivo </span></i><span style="font-size:22.5pt;mso-bidi-font-size:14.5pt; font-family:"Times New Roman","serif"">and <i><span style="font-size: 21.5pt;mso-bidi-font-size:13.5pt;font-family:"Times New Roman","serif"">in vitro </span></i><span style="font-size:22.5pt;mso-bidi-font-size:14.5pt; font-family:"Times New Roman","serif"">evaluation for immunomodulatory activity of three marine animal extracts with reference to phagocytosis </span></span>

Abstract

1399-1402<span style="font-size: 16.5pt;mso-bidi-font-size:8.5pt;font-family:" times="" new="" roman","serif""="">The whole body ether extracts of a marine prawn <span style="font-size: 15.5pt;mso-bidi-font-size:7.5pt;font-family:" arial","sans-serif""="">Nematopaleamon tenuipes <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt; font-family:" times="" new="" roman","serif""="">and two gastropods viz. Euchelus asper <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt; font-family:" times="" new="" roman","serif""="">and <span style="font-size: 15.5pt;mso-bidi-font-size:7.5pt;font-family:" arial","sans-serif""="">Hemifusus pugilinus, <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt;font-family: " times="" new="" roman","serif""="">obtained by Soxhlet extraction and cold percolation were tested for their effects on phagocytosis by <i style="mso-bidi-font-style: normal"><span style="font-size:16.0pt;mso-bidi-font-size:8.0pt;font-family: " times="" new="" roman","serif""="">in<span style="font-size:16.0pt; mso-bidi-font-size:8.0pt;font-family:" times="" new="" roman","serif""=""> vitro <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt;font-family: " times="" new="" roman","serif""="">(slide method) and by <i style="mso-bidi-font-style: normal"><span style="font-size:16.0pt;mso-bidi-font-size:8.0pt;font-family: " times="" new="" roman","serif""="">in<span style="font-size:16.0pt; mso-bidi-font-size:8.0pt;font-family:" times="" new="" roman","serif""=""> vivo <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt;font-family: " times="" new="" roman","serif""="">(carbon clearance) methods. Extract of E. asper <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt; font-family:" times="" new="" roman","serif""="">exhibits immunostimulatory activity <span style="font-size:16.0pt;mso-bidi-font-size: 8.0pt;font-family:" times="" new="" roman","serif""="">in vivo<span style="font-size:15.5pt;mso-bidi-font-size:7.5pt; font-family:" arial","sans-serif""=""> <span style="font-size:16.5pt; mso-bidi-font-size:8.5pt;font-family:" times="" new="" roman","serif""="">and immunosuppressant activity in viv<span style="font-size:15.5pt;mso-bidi-font-size:7.5pt;font-family: " arial","sans-serif""="">o. <span style="font-size:16.5pt;mso-bidi-font-size: 8.5pt;font-family:" times="" new="" roman","serif""="">The <i style="mso-bidi-font-style: normal"><span style="font-size:16.0pt;mso-bidi-font-size:8.0pt;font-family: " times="" new="" roman","serif""="">in<span style="font-size:16.0pt; mso-bidi-font-size:8.0pt;font-family:" times="" new="" roman","serif""=""> vitro <span style="font-size:16.5pt;mso-bidi-font-size:8.5pt;font-family: " times="" new="" roman","serif""="">test for <span style="font-size:15.5pt; mso-bidi-font-size:7.5pt;font-family:" arial","sans-serif""="">N. tenuipes and <span style="font-size:16.0pt;mso-bidi-font-size:8.0pt;font-family: " arial","sans-serif""="">H. <span style="font-size:15.5pt; mso-bidi-font-size:7.5pt;font-family:" arial","sans-serif""="">pugilinus shows biphasic activity, but the former shows immunostimulatory while the later shows immunosuppressant activity <span style="font-size:15.5pt;mso-bidi-font-size: 7.5pt;font-family:" arial","sans-serif""="">in vivo test. </span