<span style="font-size: 20.5pt;mso-bidi-font-size:14.5pt;font-family:"Times New Roman","serif"; color:black">Effect of genistein, a tyrosine kinase inhibitor, on TAME-esterase induced contractions <span style="font-size:21.0pt;mso-bidi-font-size: 15.0pt;font-family:"Times New Roman","serif";color:black;mso-bidi-font-weight: bold">in<b> </b><span style="font-size:20.5pt;mso-bidi-font-size:14.5pt; font-family:"Times New Roman","serif";color:black">rat aorta <i>in vitro</i> </span></span></span>

Abstract

1191-1194<span style="font-size: 14.5pt;mso-bidi-font-size:8.5pt;font-family:" times="" new="" roman","serif";="" color:black"="">Effects of genistein, a protein tyrosine kinase inhibitor, on TAME-esterase induced contractions were studied on rat aorta strips in vitro. Data showed that TAME-esterase induced contractions were concentration dependent and these contractions were significantly inhibited when rat aorta strips were pre-incubated with genistein. The present findings provide evidence for the possible contribution of tyrosine kinases during TAME-esterase induced contractions in aorta. </span