A convenient short synthesis of polysubstituted 3,4-dihydropyridine-2(1<i>H</i>)-thiones

Abstract

2563-25664-Substituted-3,4-dihydro-5-cyano-6-methyl-2(1H)-pyridones obtained in high yield in a one pot synthesis by reacting α,β-unsaturated acid chlorides with 3-aminocrotononitrile are converted quantitatively to the corresponding novel hydrogenated pyridinethiones by Lawesson's reagent