A one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline followed by synthesis of 7-methyldibenzo[<i style="mso-bidi-font-style:normal">c</i>,<i style="mso-bidi-font-style:normal">f</i>][2,7]naphthyridin-6(5<i style="mso-bidi-font-style:normal">H</i>)-ones <i style="mso-bidi-font-style:normal">via</i> three routes

Abstract

776-786An easy one pot microwave assisted synthesis of 3-acyl-2,4-dihydroxyquinoline from simple precursors followed by convenient synthesis of novel and potential HIV integrase inhibitors 7-methyldibenzo[c,f][2,7]naphthyridin-6(5H)-ones has been achieved through three different routes. Mild reaction conditions and good yields are obtained by applying microwave and photochemical techniques