Synthesis of new cyano derivatives on the basis of disubstituted indenones

Abstract

225-228<span style="font-size:15.0pt;mso-bidi-font-size:8.0pt;font-family:Fd731912-Identity-H; mso-bidi-font-family:Fd731912-Identity-H;color:#131313">2,3-Disubstituted indenones 1<span style="font-size:15.0pt;mso-bidi-font-size: 8.0pt;font-family:Fd748002-Identity-H;mso-bidi-font-family:Fd748002-Identity-H; color:#131313">a-e<span style="font-size:15.0pt;mso-bidi-font-size: 8.0pt;font-family:Fd748002-Identity-H;mso-bidi-font-family:Fd748002-Identity-H; color:#131313">, <span style="font-size:15.0pt;mso-bidi-font-size:8.0pt; font-family:Fd731912-Identity-H;mso-bidi-font-family:Fd731912-Identity-H; color:#131313">possessing substituents of <span style="font-size:15.0pt;mso-bidi-font-size:8.0pt;font-family:Fd731912-Identity-H; mso-fareast-font-family:" times="" new="" roman";mso-bidi-font-family:fd731912-identity-h;="" color:#131313;mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:="" ar-sa"=""> electron donor or electron acceptor type localised in p-position of the phenyl group, are converted into the corresponding 3-cyano-1 indanones <span style="font-size:15.0pt;mso-bidi-font-size: 8.0pt;font-family:Fd748002-Identity-H;mso-fareast-font-family:" times="" new="" roman";="" mso-bidi-font-family:fd748002-identity-h;color:#131313;mso-ansi-language:en-us;="" mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">2a-e<span style="font-size:15.0pt;mso-bidi-font-size:8.0pt;font-family:Fd748002-Identity-H; mso-fareast-font-family:" times="" new="" roman";mso-bidi-font-family:fd748002-identity-h;="" color:#131313;mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:="" ar-sa"=""> <span style="font-size:15.0pt;mso-bidi-font-size:8.0pt; font-family:Fd731912-Identity-H;mso-fareast-font-family:" times="" new="" roman";="" mso-bidi-font-family:fd731912-identity-h;color:#131313;mso-ansi-language:en-us;="" mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">by the action of KCN and (NH4)2 CO3. The structure of the products <span style="font-size: 15.0pt;mso-bidi-font-size:8.0pt;font-family:Fd748002-Identity-H;mso-fareast-font-family: " times="" new="" roman";mso-bidi-font-family:fd748002-identity-h;color:#131313;="" mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">2a-e<span style="font-size:15.0pt;mso-bidi-font-size:8.0pt;font-family:Fd748002-Identity-H; mso-fareast-font-family:" times="" new="" roman";mso-bidi-font-family:fd748002-identity-h;="" color:#131313;mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:="" ar-sa"=""> <span style="font-size:15.0pt;mso-bidi-font-size:8.0pt; font-family:Fd731912-Identity-H;mso-fareast-font-family:" times="" new="" roman";="" mso-bidi-font-family:fd731912-identity-h;color:#131313;mso-ansi-language:en-us;="" mso-fareast-language:en-us;mso-bidi-language:ar-sa"="">have been confirmed by spectral analysis.</span