976-978Hydrazone formation from salicylaldehyde and phenylhydrazine has
been studied in water-ethanol (60:40 volume) solution at 35°C and ionic
strength of 0.25 (with KCI).
The reaction exhibits specific acid (in pH<4) and general acid catalysis (in
4pHpH<4 attack of phenylhydrazine to salicylaldehyde,
and in pH>4 dehydration of
intermediate is rate detennining step. Apparent catalytic rate constants of
water and boric acid in the reaction are in good agreement with predicted values
from Bronsted relationship. The kinetic results, UV, IR and NMR spectroscopic
analyses exhibit general acid catalysis by boric acid and water.</span