A mild and efficient method for the preparation of 5'-dimethoxytrityl-2'-deoxy-nucleoside using poly(4-vinylpyridine)-costyrene

Abstract

370-371<span style="font-size:13.5pt;mso-bidi-font-size:6.5pt; font-family:HiddenHorzOCR;mso-hansi-font-family:" times="" new="" roman";mso-bidi-font-family:="" hiddenhorzocr;mso-ansi-language:en-us;mso-fareast-language:en-us;mso-bidi-language:="" ar-sa"="">5'-O-4,4'-Dimethoxytrityl-2'-deoxynucleosides have been synthesized in high yield by the reaction of 2'-deoxynucleosides with 4, 4'-dimethoxytrityl chloride in acetonitrile using poly (4- vinylpyridine)-costyrene (styrene 10%).</span