259-264In the present
study the content of phenolic compounds and flavonoids in root extract of Rhizophora
apiculata and Acanthus ilicifolius was determined, their antioxidant
property was assayed and the protective effect of R. apiculata root extract on
induced-oxidative stress was examined. R. apiculata and A.
ilicifolius root extracts were found to be rich sources of phenolic
compounds and flavonoids. DPPH free radical scavenging assay has shown that R.
apiculata has a better antioxidant activity than A. illicifolius. R.
apiculata root extract had protective effect on sodium nitrite-induced
oxidative stress in brain of rats.
The extract normalized the sodium nitrite-induced alterations in the levels of
glutathione, lipid peroxides and antiperoxidative enzymes like catalase and
superoxide dismutase. Mangrove root extract had a beneficial effect in
ameliorating oxidative stress in the brain of rats which may be attributed to
the presence of flavonoid and polyphenolic compounds