28-32Extracts of Camellia sinensis Linn.
leaves, Glycyrrhiza glabra Linn. roots and rhizome and Calendula officinalis Linn. flowers were screened for their in vitro antimicrobial
activity using agar disc diffusion method. The antimicrobial activity of
petroleum ether, dichloromethane and methanolic extracts of different parts of
these plants were studied against acne causing bacteria, namely Staphylococcus aureus (MTCC 96),
Staphylococcus epidermidis (MTCC 2639) and Propionibacterium acnes
(MTCC *1951). Methanolic extract of C. sinensis leaves possessed highest
antibacterial activity against S. epidermidis. Lowest minimum inhibitory
concentration (0.625 mg/mL) and minimum bactericidal concentration (2.5
mg/mL) against S. epidermidis were also observed for methanolic extract
of C. sinensis leaves. Phytochemical screening revealed the presence of alkaloids, flavonoids,
glycosides and terpenoids which indicates that these
phytoconstituents may be responsible for their anti-acne activity.
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